An optoelectronic holographic otoscope (OEHO) is currently in use in a major hospital. The OEHO allows for nanometer-displacement measurements of the deformation of mammalian tympanic membrane (TM) under acoustic stimulation. The optical head of the current system is sufficient for laboratory use, but requires improved optical performance and a miniaturized size to be suitable for the clinic. A new optical head configuration is designed, aided by ray tracing analysis and research of the biomechanical and optical properties of the TM. A prototype is built and the optical performance quantified via developed image processing algorithms. The device is validated through comparison of analytical, computational, and experimental results and through interferometric chinchilla TM measurements
