University Hospital for Tumors, University Hospital Center Sestre milosrdnice
Abstract
The development of diagnostic methods and screening leads to early detection of breast cancer, which is why aspirations are moving towards more conservative local treatment methods. New, non invasive and minimally invasive methods, should att ain same local control, with less cosmetic defects, side eff ects and complications compared to standard surgery. Five methods are being researched in clinical trials: cryoablation, radiofrequency ablation, laser ablation, microwave ablation and ablation by focused high intensity ultrasound waves. Although some results are promising, these methods need further technical development and prospective comparison with today’s golden standard - oncoplastic breast surgery.Razvojem dijagnostičkih mogućnosti, i probira karcinom dojke se otkriva u sve ranijem stadiju, zbog čega se teži sve poštednijim metodama lokalnog liječenja tumora. Nove, neinvazivne i minimalno invazivne metode trebale bi pružiti jednaku lokalnu kontrolu, ali uz manje kozmetske defekte, nuspojave i komplikacije u odnosu na kirurške zahvate. Trenutno je u istraživanju pet metoda: krioablacija, radiofrekvencijska ablacija, laserska ablacija, mikrovalna ablacija i ablacija fokusiranim ultrazvučnim valovima. Neke od navedenih metoda pokazuju ohrabrujuće rezultate, ali zahtijevaju dodatno tehničko usavršavanje i prospektivnu usporedbu s današnjim zlatnim standardom - onkoplastičnim kirurškim zahvatima
