Some Aspects of Isokinetic Law and Compensation Effect in Organophosphorus Compounds. Part II. Correlation Analysis of O-Alkyl-S-2-Dimethylaminoethyl Methylphosphonothiolates and Their Tetraalkylammonio Derivatives

Abstract

The correlation analysis of alkaline hydrolysis and inhihibition of BuChE with O-alkyl-S-2-dimethylaminoethyl methyl phosphonothiolates and their tetraalkylammonio derivatives are described. The logarithm dependence of the rate constants of tQ.ese reactions at two different temperatures confirms that reactions of oH- ion and of BuChE with these esters show isokinetic functions i. e. these esters form isokinetic series. The correlation analysis with different Hammets constants showed that alkoxy groups bonded to phosphours1v have somewhat greater resonance effect (a. = 1.21) in comparison to the inductive effect in alkaline h ydrolysis reaction