Scientific Unit for Clinical and Medical Research, Osijek University Hospital
Abstract
Advances in positron emission tomography (PET) techniques have allowed the measurement and imaging of serotonin synthesis, transport and receptor binding in the living human brain. Both the imaging and pathological studies in patients with epilepsy, as well as studies derived from experimental models of epilepsy provide evidence that endogenous serotonin plays a significant role in epileptogenesis. This review summarizes the advances in alpha- Methyl tryptophan PET imaging in patients with different types of epilepsy.Advances in positron emission tomography (PET) techniques have allowed the measurement and imaging of serotonin synthesis, transport and receptor binding in the living human brain. Both the imaging and pathological studies in patients with epilepsy, as well as studies derived from experimental models of epilepsy provide evidence that endogenous serotonin plays a significant role in epileptogenesis. This review summarizes the advances in alpha-Methyl tryptophan PET imaging in patients with different types of epileps
