Hypolipidemic action of oral applications of edible fats

Abstract

Levitsky A. P., Dvulit I. P., Khodakov I. V. Hypolipidemic action of oral applications of edible fats. Journal of Education, Health and Sport. 2018;8(11):600-605. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.2535711 http://ojs.ukw.edu.pl/index.php/johs/article/view/6454 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Author(s) 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 19.11.2018. Revised: 22.11.2018. Accepted: 30.11.2018. UDK 616.153:588.152:616.633:612.31 HYPOLIPIDEMIC ACTION OF ORAL APPLICATIONS OF EDIBLE FATS A. P. Levitsky 1, I. P. Dvulit2, I. V. Khodakov1 1SE «The Institute of Stomatology and Maxillofacial surgery of the National academy of medical science of Ukraine» (Odessa) 2Lviv National Medical University [email protected] Abstract Background. To determine the effect of oral fatty applications on the content of triglycerides in the serum and liver of rats. Methods. As edible fats, ordinary sunflower oil, high-oleic sunflower oil “Olivka” and butter, as well as the same oils after heat treatment, were used. Application of oils (0.5 g) on the oral mucosa was carried out once a day for 3 days. After euthanasia on the 4th day, the content of triglycerides (TG) in the serum and in the liver was determined. The content of malondialdehyde (MDA) was also determined in the liver. The ratio of the level of TG in serum and in the liver was calculated fat-incretory function of the liver. Results. Oral fatty applications cause a decrease in serum TG and increase them in the liver. In the liver, the content of MDA and the fat-incretory function decreases. Conclusion. Oral fatty applications cause hypotriglyceridemia, reduce the level of peroxidation in the liver and cause hepatosteatosis. Keywords: fat diet, oral cavity, liver, serum