Twenty eight hepatics and eight hornwort species are reported as new to Panama. Data on their habitat, local and general distribution and are included. One species, Cololejeunea panamensis G. Dauphin & Pócs is described as new to science. A new combination, Megaceros canaliculatus (Pagán) Shaw & Renzaglia, corr. et emend. J. C. Vill. & Salazar Allen, is proposed. Eight further hepatic records from the literature have been added. This raises the total number of hepatics reported from Panama to 325 species in 100 genera and 28 families
