CARNOSINE IN GENERAL

Abstract

U radu se opisuju fizikalno-kemijska svojstva dipeptida karnozina koji se nalazi u značajnim količinama u mišićima pilića. Nastaje sintezom β-alanina i L-histidina uz djelovanje enzima karnozin sintetaze. Karnozin ispoljava značajnu pufersku ak¬tivnost, posebice pri mišićnoj aktivnosti kada dolazi do acidifikacije intracelularne sredine. Posjeduje antioksidativna svojstva radi hvatanja aktivnih kisikovih specija. U posljednje vrijeme karnozin se koristi u terapeutske namjene.The paper describes physical and chemical properties of dipeptide carnosine that is found in broiler muscles in significant amounts. It is created by a synthesis of β-alanine and L-histidine along with activity of carnosine synthetase enzyme. Carnosine exhibits significant buffering activity, especially in muscle activity with occurrence of intracellular acidification. It has antioxidative properties due to capturing active oxygen species. Recently, carnosine has been used for therapeutic purpose

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