We analyzed 17 polychlorinated biphenyls (PCBs) and 7 organochlorine pesticides (OCPs) in blubber, liver, muscle, lung, heart and kidney of an adult male short-beaked common dolphin (Delphinus delphis) found dead stranded on the island of Cres (Croatia) in 2004. The PCB profile was dominated by hexachlorobiphenyls (39.4 – 63.2% of ΣPCB), with PCB-153 exhibiting the highest concentrations across all tissues. The pattern of PCB tissue distribution (ÓPCB) showed the highest burdens in blubber > liver > kidney > heart > muscle > lung, which were positively correlated with tissue lipid content (rs = 0.986, p blubber > liver > kidney > lung > heart, with no correlation to tissue lipid content (p > 0.05). Total DDTs were lower than total PCB levels for all tissues, with ΣPCB/ΣDDTs ratios ranging from 1.3 in blubber to 5.9 in muscles. Blubber OC burdens recorded in our specimen were among the highest found in a dolphin in the Mediterranean after the year 2000. This result and the presence of mono-ortho substituted PCBs with dioxin-like toxicity in all our samples may present an additional factor of concern for the conservation of regional dolphin populations.Analizirali smo 17 poliklorbifenila (PCB) i sedam organoklorovih pesticida (OCP) u potkožnom masnom tkivu, jetri, mišiću, plućima, srcu i bubregu odraslog mužjaka kratkokljunog običnog dupina (Delphinus delphis) koj je nađen nasukan na otoku Cresu (Hrvatska) 2004. godine. PCB profilom dominirali su heksaklorobifenili (39.4 – 63.2% ΣPCB), s PCB-153 utvrđenim s najvišim koncentracijama u svim tkivima. Raspodjela PCB-a u tkivima slijedi redoslijed: potkožno masno tkivo > jetra > bubreg > srce > mišić > pluća te pozitivno korelira sa sadržajem masti u pojedinom tkivu (rs = 0.986, p potkožno masno tkivo > jetra > bubreg > pluća > srce te ne pokazuje korelaciju sa sadržajem masti (p > 0.05). U svim su tkivima razine ukupnih DDT-a bile niže od razina ukupnih PCB-a, a omjeri ΣPCB/ΣDDTs u rasponu su od 1.3 u potkožnom masnom tkivu do 5.9 u mišiću. Razine organoklorovih spojeva u analiziranom uzorku potkožnog masnog tkiva među najvišim su nađenim razinama u dupinima u Sredozemnom moru nakon 2000. godine. Taj podatak te prisutnost mono-ortho supstituiranih PCB-a koji pokazuju toksičnost sličnu dioksinima u svim našim uzorcima mogu predstavljati dodatan razlog ugroženosti regionalne populacije dupina
