Faculty of Veterinary Medicine University of Zagreb
Abstract
When piglets fail to receive colostrum from the sow, as an alternative means passive immunization can be carried out with antibodies derived from non-maternal sources. In this study, pregnant cows were vaccinated intramuscularly and intramammarily with killed ETEC vaccine and developed a high level of colostral antibodies. These antibodies were specifically of IgG and IgA. Day-old piglets fed with colostrum containing a high titre of IgG survived the challenge infection. However, 75% piglets fed with colostrum from unvaccinated cows, and 100% piglets receiving no colostrum, died from challenge infection.Ako prasad nije posisala kolostrum od krmače može se pasivno imunizirati kolostrumskim protutijelima podrijetlom od krava. Steone krave bile su vakcinirane intramuskularno i intramamarno inaktiviranim enterotoksigenim sojem bakterije E. coli. U njihovu kolostrumu dokazana je visoka razina specifičnih protutijela razreda IgG i IgA. Jednodnevna prasad koja je dobila kolostrum s visokim titrom protutijela IgG preživjela je izazivačku infekciju, dok je 75% prasadi koja je dobila kolostrum od nevakciniranih krava uginulo od izazivačke infekcije. Uginula je i sva prasad koja nije dobila kolostrum
