Sestre Milosrdnice University hospital and Institute of Clinical Medical Research
Abstract
In the last four decades, the incidence of pancreatic cancer has tripled in Western countries. More than 90% of all pancreatic cancers are detected in the advanced stage of the disease when surgical treatment is no longer possible and survival after initial diagnosis is usually very short. The aim of this study was to correlate magnetic resonance imaging (MRI) established diagnosis of chronic pancreatitis, benign lesion and malignant neoplasm with final histopathology. The study included 29 patients in whom the nature of pancreatic pathology could not be determined clinically and by other imaging modalities including abdominal ultrasonography, endoscopic retrograde cholangiopancreatography and multislice computed tomography. MRI examination was performed and radiological report was compared with histopathology assessment of the pancreatic lesion detected. The data obtained indicated systematic conformity between radiological and histopathology findings, confirmed high diagnostic accuracy of MRI for selected pancreatic pathology, and demonstrated the role of MRI as a problem solving diagnostic imaging modality in undetermined pancreatic changes.U posljednja četiri desetljeća incidencija karcinoma gušterače se u zapadnim zemljama utrostručila. Više od 90% svih karcinoma gušterače otkriva se u uznapredovalom stadiju kada kirurško liječenje više nije moguće, a preživljavanje bolesnika nakon postavljene dijagnoze je najčešće vrlo kratko. Cilj istraživanja bio je usporediti nalaz magnetske rezonancije s histopatološkim nalazom promjena u gušterači u bolesnika oboljelih od kroničnog pankreatitisa te dobroćudnih i zloćudnih novotvorina gušterače. U istraživanje je uključeno 29 bolesnika kod kojih se narav patološke promjene gušterače nije mogla utvrditi klinički niti drugim radiološkim metodama koje su uključivale ultrazvučni pregled, endoskopsku retrogradnu kolangiopankreatografiju te višeslojnu kompjutoriziranu tomografiju. Podaci istraživanja upućuju na podudaranje u radiološkoj i histopatološkoj prosudbi opaženih promjena, potvrđuju visoku točnost magnetske rezonancije u dijagnostici patoloških promjena gušterače i ilustriraju njenu važnost u procjeni naravi nejasnih promjena gušterače
