Sestre Milosrdnice University hospital and Institute of Clinical Medical Research
Abstract
The aim of the study was to evaluate the efficacy of intralesional triamcinolone acetonide injection in primary and recurrent chalazion. The study included 30 patients with primary and recurrent chalazion (37 cases) and 24 patients as a control group. Patients with primary and recurrent chalazion received intralesional injection of 0.1 to 0.2 mL triamcinolone acetonide (40 mg/mL). Control group received intralesional injection of 0.1 to 0.2 mL 0.9% NaCl. Data on the lesion size, including digital color photography, lesion regression or recurrence, and complete ophthalmic examination were recorded at the time of injection and after a week or two until resolution or surgical excision. Success was defined as at least 80% decrease in size with no recurrence. Resolution of the lesion was found in 35 cases after one or two injections, with a mean time to resolution of15.27±6.12 days. Subcutaneous injection of the steroid triamcinolone acetonide in primary and recurrent chalazion appears to be a simple and efficacious therapeutic option for chalazion.Cilj studije bio je procijeniti učinkovitost intralezijskog injektiranja triamcinolon acetonida kod primarnog i recidivirajućeg halaziona. U ispitivanje je bilo uključeno 30 bolesnika s primarnim i recidivirajućim halazionom (37 slučajeva) i 24 bolesnika kao kontrolna skupina. Bolesnici s primarnim i recidivirajućim halazionom primili su intralezijsku injekciju 0,1 do 0,2 mL triamcinolon acetonida (40 mg/mL), dok su bolesnici kontrolne skupine primili intralezijsku injekciju 0,1 do 0,2 mL 0,9%-tne NaCl. Podatci o veličini lezije, uključujući digitalnu fotografiju u boji, regresiji ili recidivu lezije te o cjelokupnom oftalmološkom pregledu bilježili su se u vrijeme injektiranja te nakon jednog ili dva tjedna do povlačenja ili kirurškog odstranjenja lezije. Uspješnost je definirana kao najmanje 80%-tno smanjenje veličine lezije bez recidiva. Povlačenje lezije utvrđeno je u 35 slučajeva nakon jedne ili dvije injekcije, srednje vrijeme do povlačenja od 15,27±6,12 dana. Potkožno injektiranje steroida triamcinolon acetonida kod primarnog i recidivirajućeg halaziona pokazalo se jednostavnom i učinkovitom terapijom za halazion
