CAMPYLOBACTERS AS THE CAUSE OF ACUTE DIARRHEAL DISEASE IN THE COUNTY PRIMORSKOGORANSKA IN THE YEAR 2006

Abstract

SAŽETAK Bakterije roda Campylobacter jesu gram-negativne, zavinute, mikroaerofilne i termofilne bakterije. U humanoj patologiji najčešće su zastupljeni Campylobacter jejuni (C. jejuni) i Campylobacter coli (C. coli), i to kao uzročnici akutne dijareične bolesti nastale najčešće nakon konzumiranja nedovoljno termički obrađenoga kontaminiranoga mesa peradi ili svinja. Cilj je ovoga rada prikazati zastupljenost kampilobaktera u stolicama bolesnika s proljevom, na području Primorsko-goranske županije. Analizirani su retrospektivno podaci Laboratorija za dijagnostiku crijevnih infekcija Nastavnoga zavoda za javno zdravstvo Primorsko-goranske županije za godinu 2006. Tijekom te godine, na kampilobakter pretraženo je 6416 stolica bolesnika s akutnim proljevom. Od toga su broja iz 407 (6,34%) uzoraka izolirani kampilobakteri. Primoizolata (bolesnika) bilo je 239 (3,73%), a ostali izolati bili su ponovljene izolacije tijekom kontrole bolesnika. Među primoizolatima, C. jejuni bio je zastupljen u 187 (78,24%) slučajeva, a C. coli u 50 slučajeva (20,92%), dva izolata (0,84%) bila su identificirana jedino na razini roda kao Campylobacter spp. Najčešći bolesnici bili su mala djeca u dobi do četvrte godine, te mlađe odrasle osobe (20 – 29 godina). Najviše primoizolata bilo je tijekom mjeseca siječnja i rujna, vjerojatno zbog blage zime i toplijega kraja ljeta.ABSTRACT Campylobacter spp. are gram negative, curved, microaerophilic and thermophilic bacteria. The most important role in human pathology play Campylobacter jejuni (C. jejuni) and Campylobacter coli (C. coli) as the causative agents of acute diarrheal disease developed after consumption of contaminated meat (poultry or pork). The aim of the study was to present the quantity of campylobacters isolated from stools of the patients with diarrhea in the County Primorsko-Goranska. The data from the Laboratory for diagnostics of enteric infections of the Teaching institute of public health of the County Primorsko-Goranska for the year 2006 were analysed retrospectively. During that year 6416 stool samples were examined for Campylobacter spp. Campylobacters were found in 407 samples (6.34%) but primoisolates were identified in 239 (3.73%) patients and the other isolates were from control stools obtained from the same patients. Among primoisolates C. jejuni was found in 187 (78.24%) patients, C. coli in 50 (20.92%) patients and for two isolates (0.84%) species determination was not possible. The patients were mostly children under four years of age and young adults and the largest numbers of isolation were seen in January and September