MICROBIOLOGY OF RESPIRATORY SAMPLES FROM CHILDREN WITH CYSTIC FIBROSIS

Abstract

SAŽETAK Analizirani su retrogradno dvogodišnji (2005. – 2006.) rezultati mikrobiološke obrade respiratornih uzoraka dobivenih od bolesnika s cističnom fibrozom, liječenih u Klinici za dječje bolesti KBC-a Rijeka. Od 114 obrađenih kliničkih uzoraka, u 95,6% slučajeva kultura je bila pozitivna, a najčešći izolat bio je Pseudomonas aeruginosa (77,8%). Staphylococcus aureus izoliran u 9,6% uzoraka, dominantan je izolat u mlađe djece. Burkholderia cepacia izolirana je u samo jednome slučaju (0,6%). Dok je među testiranim sojevima vrste Pseudomonas aeruginosa najveći postotak otpornosti uočen prema gentamicinu (49,4%), netilmicinu (47,2%) i ceftazidimu (44,9%), u dvama je izolatima (2,2%) zabilježena otpornost na kolistin.SUMMARY The aim of the study was to analyze the microorganisms cultured from respiratory samples of children with cystic fibrosis treated in the Clinic for children diseases, University Hospital Rijeka, during 2005 – 2006. In 95.6% of 114 clinical samples, microbiological examination yielded positive culture. The most frequently isolated microorganisms was Pseudomonas aeruginosa (77.8%). Staphylococcus aureus was isolated in 9.6% of samples and was dominant in younger CF children. Burkholderia cepacia was isolated just in one case (0.6%). A high resistance to gentamicin (49.4%), netilmicin (47.2%) and ceftazidime (44.9%) was observed in Pseudomonas aeruginosa strains, and two of them were colistin resistant (2.2%)