Važnost otkrivanja i liječenja osoba s asimptomatskom
infekcijom klamidijom trahomatis (KT) jest u prevenciji
širenja infekcije i nastanka komplikacija infekcije u samih
tih osoba. Cilj ovog rada bio je pronaći najučinkovitiju
antimikrobnu terapiju asimptomatske urogenitalne klamidijske
infekcije. U svih je bolesnika prema listi randomizacije
primijenjena antimikrobna terapija, i to: 1) azitromicin 1 x 1,0
g, 2) azitromicin 1 x 0,5 g tijekom 6 dana; 3) doksiciklin 2 x
100 mg tijekom 7 dana i 4) doksiciklin 2 x 100 mg tijekom
14 dana. Bakteriološka ocjena djelotvornosti primijenjene terapije
procijenjena je 3-4 tjedna nakon završenog liječenja.
Kako ne postoji decidirani stav o liječenju asimptomatskih
urogenitalnih infekcija klamidijom trahomatis, to je nakon
provedenog antimikrobnog liječenja nužno provjeriti djelotvornost
provedenog liječenja.The detection and treatment of persons with
asymptomatic Chlamydia trachomatis (CT) infection is important
in preventing the infection spread and the development
of its complications. Objectives: To find the most effective
antimicrobial therapy for the treatment of asymptomatic urogenital
infection caused by Chlamydia trachomatis. The patients
were randomized into 4 groups regarding antimicrobial
therapy: 1) azithromycin 1x1.0 g in a single dose, 2) azithromycin
1x0.5 g for 6 days, 3) doxycycline 2x100 mg for 7
days, 4) doxycycline 2x100 mg for 14 days. Bacteriological
efficacy was evaluated 3-4 weeks after the end of the treatment.
There was no significant difference between the groups.
Conclusion: Since no consensus has been reached on
the treatment of asymptomatic CT urogenital infections and
different therapy regimens, we recommend that the therapy
efficacy be evaluated in every single case by one of the standardized
microbiological methods
