The most frequent contact allergens in patients with contact dermatitis in the Slavonski Brod region

Abstract

Cilj je ovog rada bio prikazati rezultate epikutanog testa standardnom serijom alergena na Odjelu za kožne i spolne bolesti Opće bolnice "Dr. Josip Benčević" u Slavonskom Brodu tijekom protekle dvije godine te ih usporediti s rezultatima testiranja u Alergološkoj ambulanti Klinike za kožne i spolne bolesti u Zagrebu i rezultatima testiranja brojnih inozemnih autora. Rezultati epikutanog mjesta standardnom serijom od 20 alergena uspoređivani su između Klinike za kožne i spolne bolesti, te Opće bolnice "Dr. Josip Benčević". Kroz 24 mjeseca ispitanici alergološke ambulante Odjela za kožne i spolne bolesti u Slavonskom Brodu testirani su standardnom serijom. Na Klinici za kožne i spolne bolesti na istu seriju alergena testirani su bolesnici u petogodišnjem periodu. Od naših bolesnika 172 su imala pozitivne reakcije, od toga 88 jednu pozitivnu reakciju, 60 dvije pozitivne reakcije, te 24 tri i/ili više pozitivnih reakcija. Najčešće pozitivne reakcije imali smo na nikal sulfat, kao što je vidljivo i u rezultatima Alergološke ambulante Klinike za kožne i spolne bolesti. Statistički značajne pozitivne reakcije zabilježene su kod tri alergena: nikal sulfat, kobalt klorid i smjesa mirisa. U našem dvogodišnjem praćenju učestalost pozitivnih epikutanih testova na nikal sulfat, formaldehid, Quarternium 15, te timerosal je podjednaka, dok je kod smjese mirisa, neomycin sulfata, kobalt klorida i peruanskog balzama nešto niža.The goal of this paper is to show the results of the epicutaneous (patch) test with standard allergens at the Department of Dermatology and Venerology of General Hospital "Dr. Josip Benčević" in Slavonski Brod in the past two years. The goal is also to compare these results with the results from the Allergological Infirmary in the Department of Dermatology and Venerology in Zagreb University Hospital Center. The results of patch testing with 20 standard allergens from General Hospital "Dr. Josip Benčević" and from the Department of Dermatology and Venerology in Zagreb University Hospital Center have been compared. In our "Dr, Josip Benčević" Hospital patients were tested during 2004 and 2005. In the Department of Dermatology and venerology in Zagreb University Hospital Center patients were tested in a five-year period. There were 172 patients with positive test results, out of which 88 had one positive reaction, 60 had two positive reactions, and 24 had three or more positive reactions. NiSO4 (or Nickel-sulfate) was the most common cause for the positive test reaction. The same compound was also the most common cause in the Department of Dermatology and Venerology in Zagreb University Hospital Center. Statistically significant positive reactions were present in three allergens: nickel sulfate, cobalt chloride and fragrance mix. In the two-year follow up (monitoring) frequency of epicutaneous (patch) test positive reactions on nickel sulfate, formaldehyde, Quarterinum-15 and Thimerosal is almost the same, while the frequency of positive reactions on fragrance mix, neomycin sulfate, cobalt chloride and balsam of Peru is somewhat lower

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