Curcumin Ag nanoconjugates for improved therapeutic effects in cancer

Abstract

Darshini Shah, Reema Savaliya, Pal Patel, Krupa Kansara, Alok Pandya, Alok Dhawan, Sanjay Singh Institute of Life Sciences, School of Science and Technology, Ahmedabad University, Ahmedabad, Gujarat, India Abstract: Curcumin has a broad spectrum of pharmacological activities, one of them is anticancer activity that is mediated through multiple mechanisms. The major disadvantage associated with the use of curcumin is its low bioavailability due to its poor aqueous solubility. Nanoformulations of curcumin provide an effective solution for this problem. In this study, we have synthesized curcumin Ag nanoconjugates and evaluated their anticancer potential. Keywords: curcumin, anticancer, nanoconjugate, AgNP