Introduction: The introduction of implantable devices in the human body determines a series of issues
regarding their long-term tolerance. The biological tests represent the most critical stage in the biocompatibility
assessment. Purpose of the Study: We proposed the testing of various materials that might be used in the
development of implantable devices that function as auditory sensors. Materials and Methods: We conducted
in vivo tests (on experience animals – white rats) for the biocompatibility of magnetostrictive materials based on
FeGa20 and Co75Fe10B15. We implanted a sample from each material in the interface of the subcutaneous
cellular tissue and paravertebral muscles. The biochemical and cellular modifications and also the immune
response are evaluated at 14, 60 and 120 days from the implantation. Results: The results at 14, 60 and 120 days
were similar for the both types of implanted materials: normal teguments (epidermal tissue of normal thickness,
numerous hair follicles, dermal and hypodermal tissues without any modifications) and a normal layer of
skeletal muscle fibers. Discussions: The material biocompatibility was assessed by histological examination of
the organsim reaction to the implantated foreign body. The lack of biocompatibility is characterised by acute or
chronic inflammatory reaction at the site of implantation, with the presence of inflammatory cells as the
determinant criteria. Conclusions: Based on the prelevated histological materials examined macroscopically and
microscopically we can conclude that, after 3 succesive tests, the evaluated materials (FeGa20, Co75Fe10B15)
are biocompatible