The aim of the article is to analyze methods to assess the efficiency of international technical assistance (ITA) and determine its real impact on economic transformations in Ukraine and its regions. Having examined a significant array of statistical data, scientific papers, there revealed trends in changes in the volume of and priority sectors for financing projects and programs of the ITA, taking into account political and economic transformations in the life of the country. There proposed approach to evaluating the efficiency of ITA based on determining the coefficient of correlation among the volumes of ITA in a particular sector of the economy, its share in the country’s GDP and individual sectoral indicators. Its evaluation for industries that are currently under reform (transport and infrastructure, health care and medicine, energy, the sectors of agricultural and education) has once again confirmed the conclusions of many scientists on the lack of clear correlation among the variables studied, which indicates multicriteriality, ambiguity and complexity of the impact of the ITA on the economic development of the country. Prospects for further research in this direction, given the ambiguity of the impact of ITA programs and projects on the development of the country, are in improving the system for monitoring projects by the authorities and local governments as well as in using modern analytical methods, simulation, system dynamic simulation, etc
