Comparing the Growth Pattern of the First 5-Year Life in Children with Congenital Hypothyroidism in Yazd According to Growth Pattern of Normal Children of World Health Organization in 2014: A Cohort Study

Abstract

Abstract Introduction: Congenital hypothyroidism is regarded as one of the major preventable and treatable causes of physical disorders. Therefore, the present study aimed to study the growth pattern of first 5-year life in children with congenital hypothyroidism in Yazd according to growth pattern of healthy children of World Health Organization (WHO). Methods: This descriptive retrospective cohort study was performed on all the infants born within 2006- 2008, that had been diagnosed as a patient by a screening program. After taking inclusion and exclusion criteria into account, growth pattern of the infants' height, weight and head circumference within first 5-year of life was compared to that of normal children of WHO in terms of age and sex in 3,15,50,85, 97 percentiles. Results: The study results revealed that pattern growth of height, weight and head circumference within girl patients was developed parallel with the growth pattern of healthy girls of WHO. Within the boys, linear pattern growth after 36 months, weight growth after 9 months and head circumference growth at 24 months was similar to the growth pattern of healthy boys of WHO. Conclusions: The growth pattern in children with congenital hypothyroidism will develop towards normal growth pattern after treatment and medical care continuation