Introduction: Primary percutaneous coronary intervention (PPCI) is a gold standard in treating patients with acute myocardial infarction (AMI) with ST Elevation Myocardial Infarction (STEMI). Aim: The aim of this study is to evaluate the impact of diabetic status three year survival in patients with STEMI treated with PPCI on admission. Material and methods: We analyzed 499 STEMI patients treated with primary PCI, from a prospective, electronic database of the Clinical Center of Serbia Catheterization Laboratory -that contains patient records from 2009 to 2016. Patients were divided into 2 groups: patients with diabetes mellitus (DM) and those without DM. Results: Our results showed that 416 (83,4%) patients did not have DM and 83 (16,6%) had DM. There was a statistically significant difference in mortality rate among two groups after 30 days and 3 years after intervention (DM 13,3% vs without DM 4,1%, p=0,003 after 30 days; DM 21,7% vs without DM 10,6%, p=0,010 after 3 years). However, when adjusted for other baseline risk factors, DM was not an independent predictor of 3-year mortality (HR=1,275, 95% CI 0,652-2,494, p=0,478). Conclusion: Patients with DM had higher mortality rates in both short-term and long-term follow-ups after PPCI