Community and Hospital Acquired Staphylococcal Infections in Adults

Abstract

Clinical and laboratory findings and therapeutical features of 76 patients with staphylococcal infection have been evaluated. Staphylococcus aureus was isolated in 53 (70%), and coagulase negative staphylococci (CNS) in 23 (30%) patients. Methicillin resistance was found to be 8 (15%) among the S. aureus isolates and 12 (52%) among CNS. Fourtysix of 76 (61%) patients had an underlying disease. Eighteen (34%) patients with infection due to S. aureus and 18 (78%) patients with infection due to CNS had hospital acquired infection. Fourtysix of 76 (61%) patients were diagnosed as sepsis, 23 (30%) soft tissue infection, 4 (5%) endocarditis, 2 (3%) pneumonia, I (I%) pleural empyema. Primary site of infection was soft tissue in 32 % of patients with S. aureus sepsis and intravenous catheter in 94% of patients with coagulase negative staphylococcal sepsis. Antimicrobial therapy was determined according to severity of disease and methicillin resistance of strain. Vancomycin therapy was given in 22 patients. Three of 76 (4%) patients developed different complications and three patients recovered with some sequelae. Seven of 76 (9%) patients died