Crystal Stinson

Larry L. Bellinger

Mahesh Rao

Michael B. Yee

Paul R. Kinchington

Phillip R. Kramer

Frontiers in Integrative Neuroscience

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CORRECTIONpublished: 31 January 2019doi: 10.3389/fnint.2018.00066Frontiers in Integrative Neuroscience | www.frontiersin.org 1 January 2019 | Volume 12 | Article 66Edited and reviewed by:Vinay V. Parikh,Temple University, United States*Correspondence:Phillip R. Kramerpkramer@tamhsc.eduReceived: 03 December 2018Accepted: 13 December 2018Published: 31 January 2019Citation:Kramer PR, Rao M, Stinson C,Bellinger LL, Kinchington PR andYee MB (2019) Corrigendum:Aromatase Derived Estradiol Withinthe Thalamus Modulates Pain Inducedby Varicella Zoster Virus.Front. Integr. Neurosci. 12:66.doi: 10.3389/fnint.2018.00066Corrigendum: Aromatase DerivedEstradiol Within the ThalamusModulates Pain Induced by VaricellaZoster VirusPhillip R. Kramer 1*, Mahesh Rao 1, Crystal Stinson 1, Larry L. Bellinger 1,Paul R. Kinchington 2 and Michael B. Yee 21Department of Biomedical Science, Texas A&M University College of Dentistry, Dallas, TX, United States, 2Department ofOphthalmology and of Molecular Microbiology and Genetics, Eye and Ear Foundation, School of Medicine, University ofPittsburgh, Pittsburgh, PA, United StatesKeywords: orofacial, herpes zoster, neuralgia, shingles, pain, estrogen, aromatase, thalamusA Corrigendum onAromatase Derived EstradiolWithin the ThalamusModulates Pain Induced byVaricella ZosterVirusby Kramer, PR., Rao, M., Stinson, C., Bellinger, L. L., Kinchington, P. R., and Yee, M. B. (2018). Front.Integr. Neurosci. 12:46. doi: 10.3389/fnint.2018.00046In the original article, there was a mistake in Figure 3 as published. The value of “mg” should havebeen “µg.” The corrected Figure 3 appears below. A correction has also been made to the Materialand Methods, Enzyme-linked immunosorbent assay (ELISA).“Fresh thalamic tissue punches from all five animals in experiment #3 (Table 1) was storedin liquid nitrogen until analysis. Tissue was placed in 250 µl of T-Per tissue protein extractionreagent containing Halt Protease Inhibitor and ground (Thermo Scientific, Rockford, IL, USA).Ground samples were frozen and thawed, followed by centrifugation and decanting of thesupernatant. Quantitation of VGAT in the supernatant was completed on duplicate 100 µl samplesof supernatant using an SLC32A1 (VGAT) ELISA following themanufacturer’s directions (Cusabio,catalog #CSB-EL021578MO). Total protein was determined in each sample using a BCA proteinassay (Thermo Scientific, Waltham, WA, USA). Values represent the pg of VGAT per µg of totalprotein.”Additionally, the middle initial was missing in the first author’s name. This has been correctedfrom “Philip Kramer” to “Philip R. Kramer.”The authors apologize for this error and state that this does not change the scientific conclusionsof the article in any way. The original article has been updated.Conflict of Interest Statement: The authors declare that the research was conducted in the absence of any commercial orfinancial relationships that could be construed as a potential conflict of interest.Copyright © 2019 Kramer, Rao, Stinson, Bellinger, Kinchington and Yee. This is an open-access article distributed under theterms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted,provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited,in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply withthese terms.Kramer et al. Orofacial Pain MechanismsFIGURE 3 | Vesicular GABA transporter (VGAT) expression in the thalamuswas significantly reduced after infusing letrozole 5 mg/ml into the thalamus.Animals were sacrificed after the second week of place escape/avoidanceparadigm (PEAP) testing. In panel (A), real time polymerase chain reaction(RT-PCR) was completed after isolating thalamic plugs (four animals per group)and in panel (B) VGAT protein was quantitated after isolating thalamic plugs byenzyme-linked immunosorbent assay (ELISA; five animals per group). Theasterisks indicate a significant difference of p < 0.05. Values are means andSEM.Frontiers in Integrative Neuroscience | www.frontiersin.org 2 January 2019 | Volume 12 | Article 66

Corrigendum: Aromatase Derived Estradiol Within the Thalamus Modulates Pain Induced by Varicella Zoster Virus

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Corrigendum: Aromatase Derived Estradiol Within the Thalamus Modulates Pain Induced by Varicella Zoster Virus

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