Nosocomial infection surveillance using standard surveillance method and standard definitions is necessary to determine problems and to take appropriate infection control precautions. A good organization including infection control committee set up is essential to reach this aim. It is hard to apply infection control precautions in the hospitals and countries with limited resources. The main problems are; lack of training, lack of quality and quantity of the personnel, limited enforcement of hospital infection control committee, inadequate awareness of hospital staff, HCW in the hospital infection control perform efforts as an additional task, tasks of hospital infection control committee were not defined well, failure or under-application of legal bases, lack of administrative supports, lack of separate budget for infection control, inadequate conformity with the architectural structure for hospital infection control (isolation, etc.), presence of a crowded hospital and patient rooms, inability to provide adequate tools and materials for infection control, lack of national guidelines for infection control. This review emphasis on organization of hospital infection control measures in the hospitals and countries with limited resources