EPIDEMIOLOGICAL AND CLINICAL PECULIARITIES OF ATOPIC DERMATITIS IN CHILDREN IN ENDEMIC REGION WITH OPISTHORCHIASIS

Abstract

The cross-sectional study of schoolchildren from Tomsk (the region with low prevalence of opisthorchiasis) and Tomsk region (rural places with high prevalence of opisthorchiasis) with Russian version of standardized questionnaire ISAAC was performed. The study included questionnaire poll and allergological diagnostics with standardized panel of allergens. Prevalence of atopic dermaitits (AtD) symptoms was not differing, but the peculiarities of clinical course of disease were revealed depending on the place of living and gender. The onset of AtD was earlier in schoolchildren from Tomsk compared to schoolchildren from rural places. Despite the absence of statistically significant differences in symptoms’ prevalence, the level of sensitizing in children from the city was much higher than in village (60% and 30% correspondingly, p<0,001). This fact shows modification of allergic inflammation during opisthorchiasis invasion and it needs further study.Key words: children, atopic dermatitis, ISAAC, Opisthorchis felineus, sensitisation.(Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(3):50-53