Osteogenesis stimulation is one of the underinvestigated issues nowadays, as well as the topical problem of traumatology. One of the most important functions of the osseous tissue is depositing of macro- and microelements, due to this research on the skeleton ion profile is highly important to explain the osteogenesis physiological and reparative processes. As some microelements are involved into enzyme catalysis reactions, which are held in the osteogenic cells, so in case of their deficit or imbalance some processes are interrupted such as osteoblastic and osteoclastic differentiation, apatite crystallization process, cell-cell collaboration. These all cause physiological and reparative remodeling changes of bone.
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