Scientific Сentre for Family Health and Human Reproduction Problems
Abstract
The following groups were examined under clinical condition: the 1st group (47 persons) - the employees with a long work period working at the Joint-Stock Company "Sayanskchimplast" exposed to mercury compound. The mean age - 49,2 ± 4,4 years old, the mean working period -18,1 ± 5,6 years. The 2nd group (51 persons) consisted of the employees working at the Joint-Stock Company "Usolyechimprom" in Irkutsk Region with the diagnosis of chronic mercury intoxication (CMI), the mean age - 42,7 ± 4,3 years old and the mean time period of exposure to mercury - 12,3 ± 2,7 years. The postcontact period amounted 8,5 ± 2,6 years. The examination data of 26 persons (males) who were not exposed to the harmful production factors were used as the control one. All the persons examined were subjected to the ultrasonic dopplerography of the extracranial vessels and the registration of the somatosensoric induced potentials. This study allowed to assess the state of the cerebral hemodinamics manifested as the autoregulation disorder of the brain bloodflow along the metabolic contour in the employees examined in both groups. It should be noted the presence of the change correlation in the state of the central afferent inductive structures consisting in growing the time period of the central conductive capability, that is, the conductance from the lower sections of the stem up to the brain cortex and the functional change in the metabolic diameter regulation of the cerebral vessels in the patients exposed to the metallic mercury at the production. As compared with the control the more expressed index change of the somatosensoric induced potentials were registered in the subgroup of the patients in the postponed period of chronic mercury intoxication with the revealed regulation disorders of the cerebral vessels. The change were found to correlate with the impulse conductance disorders at the level of the thalamic and cortical structures. The attention should be paid that the change revealed were registered in the group of the patients exposed to the metallic mercury at the production but without the revealed diagnosis of chronic mercury intoxication with allow to consider the presence of the changes in the state of the conductive structures in this group of the patients examined
