A computational study is conducted to explore the effect of vertical wall suction or blowing on two-dimensional confined wall jet hydrodynamic characteristics. Using an implicit finite volume technique in Cartesian coordinate system, several parameters have been investigated for a wide range of Lewis numbers by fixing the Prandtl number at 7 that corresponds to water. The main purpose is to analyze the control size and location effectiveness on the flow pattern as well as heat and mass transfer rates. Detailed numerical simulations demonstrated that as the local blowing is moved downstream, discrete vortex formation begins at a critical location then shedding phenomenon occurs behind the slot at advanced positions. Since the flow dynamic structure is mainly altered, averages skin friction and thermo-solutal coefficients distributions are largely influenced. Approximately for x_s≤4 (upstream of the natural vortex emission position), Nusselt and Sherwood numbers slightly increase with the control location x_s. However, they gradually decrease as the blowing slot approaches the domain exit. Optimum values were obtained when locating the slot just downstream of the uncontrolled Kelvin-Helmholtz instability onset. Furthermore, computations illustrated that an appropriate suction slot length selection could be a simple and efficient tool to delay or even suppress natural structure emission and development. This choice is essentially related to the recirculation cell size