Prolonged standing is one of the crucial occupational risk factors that contributes to discomfort, fatigue, and in the
long-term can cause work-related musculoskeletal disorders (WMSDs) among workers. The objective of this article is to
disseminate information about the effect of prolonged standing, which can cause muscle discomfort, fatigue, and WMSDs.
Prolonged standing without sufficient rest can lead to muscle discomfort, and eventually to fatigue, especially in the back and
lower extremities of a worker’s body. Prolonged standing without any form of intervention could lead to musculoskeletal
disorders among workers. This review shows that the level of body comfort among workers in Malaysia is inadequate due to
several factors of which prolonged standing is one. Therefore, ergonomic interventions are crucial to ensure the safety, welfare,
and health of workers in the workplace