We did not find sufficient evidence to conclude that any of our three interventions impacted occupational performance, which is the basis of occupational therapy. Multiple were designed for diagnoses other than Autism Spectrum Disorder and were not designed with occupational engagement as a goal. In addition, two of the interventions, the Wilbarger Protocol and Therasuit, were not reviewed by any of the expert review groups. In order for conclusions to be made about the effectiveness and efficacy of these interventions, thorough, high-quality research is needed. We do not recommend the use of the Wilbarger Protocol, Therasuit, or CranioSaccral Therapy as comprehensive treatments in clinical occupational therapy practice at this time