Nouveaux procédés de microscopie tridimensionnelle et algorithmes de traitement et quantification d'images pour étudier les modèles biologiques associés au cancer

Abstract

Recent progresses in 3D microscopy technologies revolutionise our way to study fundamental biological processes involved in cancer metastasis. We considered several in vitro and in vivo biological models, used various microscopy techniques and developed adapted processing, characterisation and quantification algorithms to study migration, invasion, angiogenesis lymphangiogenesis processes by analysing cell-to-cell and cell-to-matrix interactions