Pulpitis is inflammation of soft tissues of dental cavity caused by pathogenic microorganisms that penetrate mostly through the carious cavity. The purpose of the research was to study morphological changes of dental pulp in experimental deep caries with perforation of the pulp chamber in rats. In the coronal and cervical portions of the pulp in deep caries with perforation of pulp chamber irreversible necrotic processes of odontoblasts have been noted. At the same time significant circulatory disorders in the form of thrombosis and hemorrhage have been detected in the root portion of pulp. Moreover, necrobiotic changes in the root portion of the pulp are combined with the inflammatory infiltrates, which can further affect periodontium
