The effects of radiation on an operational amplifier were investigated through simulation. The μA 741 was simulated using Spice. Under normal conditions the 741 had the following properties: offset Voltage (Vos) of 0.8 mV, bias current (IB) of 27 nA, offset current (Ios) of 1 nA, and an open loop gain (A0.1.) of 112 dB. When exposed to neutron fluence of 5 x 10¹³ n/cm², these parameters changed to offset voltage of 45 mV, bias current of 1500 nA, offset current of 500 nA, and an open loop gain of 66 dB. A new circuit is proposed that provides improvements in the above parameters. The modified circuit gives a Vos of 3 mV, IB of 200 nA, Ios of 34 nA and A0.1. of 93 dB following exposure to a neutron fluence of 5 x 10¹³n/cm²