The isolation and crystal structure of a cyclic selenenate ester derived from bis(2,6-diformyl-4-tert-butylphenyl)diselenide and its glutathione peroxidase-like activity
Enzyme mimicry: Halogenation of diselenide 1 affords the cyclic selenenate ester 2 (see scheme) through a highly unstable selenenic acid intermediate. Compound 2 exhibits a strong intramolecular nonbonding Se···O interaction. Both 1 and 2 show excellent glutathione peroxidase-like catalytic activity
