Toxicity and late effects

Abstract

One in 1000 young adults is a cancer survivor, 10-15 percent of whom originally had a brain tumor. Thus, quality of life and any resulting long-term disabilities in these individuals have become important public health issues. Despite the recognition of endocrine, neurological, and cognitive deficits, there is little understanding of the underlying pathology or its evolution, whilst community awareness of potential secondary disease and/or remedial help is often limited. Early (and even preventive) psychological and rehabilitative intervention to improve not only physical and hormonal health but also social, educational, and independence skills may make the difference between an institutionalized, unhealthy, short life, and a fuller, independent adult life.</p