Review of: Roy PM, Corsi DJ, Carrier M, et al. Net clinical benefit of hospitalization versus outpatient management of patients with acute pulmonary embolism. J Thromb Haemost. 2017;15:685-694.3 pagesWhat's the best treatment setting for stable PE patients? The answer seems to be the outpatient setting. Here's why. PRACTICE CHANGER: Manage patients with acute pulmonary embolism (PE) who are hemodynamically stable in the outpatient setting to decrease adverse events--regardless of their initial risk category. STRENGTH OF RECOMMENDATION: B: Based upon a good-quality retrospective cohort propensity score analysis.Authors: Monica Schaffer, MD; Gregory Castelli, PharmD, BCPS, BC-ADM UPMC St. Margaret, Pittsburgh, Pa