Human Computer Interaction (HCI) is a design-oriented research field, articulating and contributing to design knowledge. This research field has its own perspective of what a relevant design solution is or which design methods that are suitable, which does not necessarily match how for example industrial designers would understand or describe design. We aim to extract the core of design as an activity, in order to clarify what design skills may involve. This paper describes design activities, and articulates how negative space as an artistic skill is a prerequisite to achieve re-framing a design situation and to facilitate successful co-creation of wicked design challenges. The notion of negative space is traditionally associated to art and perception, for example used in professional practices in music, art and design. We illustrate how making use of negative space supports avoiding design fixations, and increase the chance of successfully addressing wicked design problems, such as sustainable solutions for societal challenges. We argue that HCI research would benefit from understanding and applying negative space in design challenges and illustrate how this can be done
