Data related to the publication: "Imaging Mass Cytometry Analysis
Sheds Light on Type 1 Diabetes Progression" (manuscript submitted to Cell Metabolism).
We used imaging mass cytometry to simultaneously image 37 biomarkers with single-cell and spatial resolution in pancreas sections from 12 human donors at different stages of type 1 diabetes.
CODE:
- Python script for coordinate transformation
- Functions for custom histoCAT neighborhood analysis
DATA:
- Single-cell data
- Islet-level data
- Relationships between cells and islets
IMAGES:
- Image stacks (37 channels) for all areas imaged (numbers indicate nPOD case IDs)
- Panel file with information related to antibodies and metal tags
- Metadata file with patient information for all image