Right venticular loading conditions in left ventricular assist device recipients

Abstract

A ventricular assist device is a type of mechanical circulatory support used in patients with advanced heart failure. Left ventricular assist devices (LVAD) can be used as destination therapy, where they are an alternative to heart transplantation, bridge to transplant therapy or bridge to recovery therapy. The most common complication in the immediate postoperative period after LVAD implantation is right ventricular failure. It is challenging to determine which patients may develop right ventricular failure in the postoperative period, and there is no equivocal evidence in the literature suggesting which parameters might be optimal in predicting right ventricular failure (RVF). The aim of this study was to identify and obtain clinical, hemodynamic and echocardiographic parameters that could successfully predict RVF in LVAD recipients. For this we have studied 40 consecutive patients at the University Hospital Centre Zagreb in which we have measured parameters of heart geometry and function by echocardiography, as well as functional and hemodynamic values by right heart catheterization which were used in combination with clinical parameters for the prediction of early and late RVF

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