Objectives
To determine whether 3D acquisitions provide equivalent image quality, lesion delineation quality and PI-RADS v2 performance compared to 2D acquisitions in T2-weighted imaging of the prostate at 3 T.
Methods
This IRB-approved, prospective study included 150 consecutive patients (mean age 63.7 years, 3584 years; mean PSA 7.2 ng/ml, 0.431.1 ng/ml). Two uroradiologists (R1, R2) independently rated image quality and lesion delineation quality using a five-point ordinal scale and assigned a PI-RADS score for 2D and 3D T2-weighted image data sets. Data were compared using visual grading characteristics (VGC) and receiver operating characteristics (ROC)/area under the curve (AUC) analysis.
Results
Image quality was similarly good to excellent for 2D T2w (mean score R1, 4.3 0.81; R2, 4.7 0.83) and 3D T2w (mean score R1, 4.3 0.82; R2, 4.7 0.69), p = 0.269. Lesion delineation was rated good to excellent for 2D (mean score R1, 4.16 0.81; R2, 4.19 0.92) and 3D T2w (R1, 4.19 0.94; R2, 4.27 0.94) without significant differences (p = 0.785). ROC analysis showed an equivalent performance for 2D (AUC 0.5800.623) and 3D (AUC 0.5760.629) T2w (p > 0.05, respectively).
Conclusions
Three-dimensional acquisitions demonstrated equivalent image and lesion delineation quality, and PI-RADS v2 performance, compared to 2D in T2-weighted imaging of the prostate. Three-dimensional T2-weighted imaging could be used to considerably shorten prostate MRI protocols in clinical practice.
Key points
3D shows equivalent image quality and lesion delineation compared to 2D T2w.
3D T2w and 2D T2w image acquisition demonstrated comparable diagnostic performance.
Using a single 3D T2w acquisition may shorten the protocol by 40%.
Combined with short DCE, multiparametric protocols of 10 min are feasible.(VLID)357502
