Intestinal diseases are often the consequence of a myriad factors which disturb
the complex ecosystem of the gastrointestinal system. For that reason, great
attention is dedicated to the use of lactic acid bacteria as probiotics. When
choosing the strains for probiotic use, one of the important criteria is the ability
of adhesion and binding to the intestinal epithelium. Therefore, the aim of this
study was to examine the possibility of adhesion and colonization of
Lactobacillus plantarum strain S1 to gastrointestinal system of mice. At the
same time the influence of L. plantarum S1 on composition of intestinal
microflora of mice was examined. To test the in vitro adhesion properties,
bacteria were added to freshly prepared tissue of the BALB/c mice small
intestine. Mice were fed with L. plantarum strain S1 for 5 consecutive days.
The result showed that L. plantarum strain S1 have good adhesion ability, in
vitro and in vivo. The examined strain of L. plantarum successfully colonize the
gastrointestinal system of mice and it showed a positive effect on the intestinal
microflora, reducing the number of enterobacteria and clostridia.
In conclusion, L. plantarum strain S1 shows good properties of adhesion and
colonization of the gastrointestinal system of mice and for that reasons could
be used as a probiotic strain