University of Zagreb. Faculty of Chemical Engineering and Technology.
Abstract
Cilj ovog rada je sinteza i optička karakterizacija novih elektron donorsko-akceptorskih 1,3- i 1,4-bis(kumarin-triazolil) derivata benzena kao potencijalnih pH probi i senzora za metalne ione. Spojevi 3 i 4 uspješno su sintetizirani reakcijama klasične organske sinteze i click reakcijom alkina i azida. Strukture svih priređenih spojeva potvrđene su 1H-NMR spektroskopijom. Ciljani spojevi su okarakterizirani UV-vidljivom apsorpcijskom i fluorescencijskom spektrofotometrijom. Spektroskopska svojstva spojeva ispitana su u otopinama univerzalnog pufera i etanolu u rasponu vrijednosti pH od 1 do 13. Ispitan je utjecaj otapala različitih parametara polarnosti na spektralna svojstva novopripravljenih spojeva, kao i ovisnost intenziteta fluorescencije spojeva 3 i 4 u otopini etanola o različitim ionima metala u svrhu primjene ciljanih spojeva kao potencijalnih senzora za metale. Radi promjene spektrofotometrijskih svojstava u prisutnosti iona željeza i bakra spojevi 3 i 4 imaju potencijalnu senzorsku primjenu.Aim of this work was synthesis and optical characterization of novel electron donor-acceptor bis(coumarin-triazolyl)benzene derivatives featuring coumarin and 1,2,3-triazole moiety in pH and metal ion sensing. Compounds 3 and 4 were successfully synthesized by combination of classical synthetic approach and click reaction. The structures of novel synthesized compounds were determined by means of 1H-NMR spectroscopy. The target compounds were characterized by UV-Visible absorption and fluorescence spectrophotometry in the universal buffer and ethanolic solutions in the pH range 1 to 13. The concentration of the tested compound was 1×10^-5 M for all measurements. The effect of solvent polarity was also studied. The influence of various metal ions on the fluorescence spectra was examined in ethanol solutions. The presence of metal ions caused changes in spectra of compounds 3 and 4 making them interesting for further studying in metal ion sensing
