Bente Gammelgaard

Bjørn Schmidt

Canepari

Carraher, Jr

Claus Hansen

de Flores

de Gregori

El-Toufaili

Erik H. Larsen

Filella

Foster

Franco

Frézard

Hansen

Helle Rüsz Hansen

Krachler

Ledwith

Lintschinger

Miekeley

Miller

Miravet

Moesby

Santos

Saunders

Schulz

Stefan Stürup

Wehmeier

World Health Organization

Zheng

Crossref

The Analyst

Quantitative HPLC-ICP-MS analysis of antimonyredox speciation in complex sample matrices: new insights into the Sb-chemistry causing poor chromatographic recoveries

Hansen, Claus

Schmidt, Bjørn

Larsen, Erik Huusfeldt

Gammelgaard, Bente

Stürup, Stefan

Hansen, Helle Rüsz

Copenhagen University Research Information System

Quantitative HPLC-ICP-MC analysis of antimony redox speciation in complex sample matrices: new insights into the Sb-chemistry causing poor chromatographic recoveries

In solution antimony exists either in the pentavalent or trivalent oxidation state. As Sb(III) is more toxic than Sb(V), it is important to be able to perform a quantitative speciation analysis of Sb’s oxidation state. The most commonly applied chromatographic methods used for this redox speciation analysis do, however, often show a low chromatographic Sb recovery when samples of environmental or biological origin are analysed. In this study we explored basal chemistry of antimony and found that formation of macromolecules, presumably oligomeric and polymeric Sb(V) species, is the primary cause of low chromatographic recoveries. A combination of HPLC-ICP-MS, AFFF-ICP-MS and spinfiltration was applied for analysis of model compounds and biological samples. Quantitative chromatographic Sb redox speciation analysis was possible by acidic hydrolysis of the antimony polymers prior to analysis. Sample treatment procedures were studied and the optimum solution was acidic hydrolysis by 1 M HCl in the presence of chelating ligands (EDTA, citrate), which stabilise the trivalent oxidation state of Sb

Online Research Database In Technology

Quantitative HPLC-ICP-MS analysis of antimony redox speciation in complex sample matrices: new insights into the Sb-chemistry causing poor chromatographic recoveries

http://orbit.dtu.dk/ws/files/5595171/81B37d01.pdf

Quantitative HPLC-ICP-MS analysis of antimony redox speciation in complex sample matrices: new insights into the Sb-chemistry causing poor chromatographic recoveries

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Copenhagen University Research Information System

Online Research Database In Technology