CORE
🇺🇦
make metadata, not war
Services
Services overview
Explore all CORE services
Access to raw data
API
Dataset
FastSync
Content discovery
Recommender
Discovery
OAI identifiers
OAI Resolver
Managing content
Dashboard
Bespoke contracts
Consultancy services
Support us
Support us
Membership
Sponsorship
Community governance
Advisory Board
Board of supporters
Research network
About
About us
Our mission
Team
Blog
FAQs
Contact us
An accurate simplified data treatment for the initial adsorption kinetics in conditions of laminar convection in a slit: Application to protein adsorption
Authors
Déjardin P.
Vasina E.
Publication date
1 January 2004
Publisher
Abstract
We present the derivation of a simple approximation for the original expression of the adsorption rate [Langmuir 10 (1994) 3898] in conditions of laminar flow in a slit, to relate the measured initial kinetic constant k with the interfacial kinetic constant ka and the transport-limited Lévêque constant kLev. The same method of derivation is applied here to get a simple approximation of the average kinetic constant 〈k〉 [Biomaterials 20 (1999) 1621]. For the local value, at distance x from the entrance of the slit, we propose k(x)/ka=(u-1)(au-1)/(bu+1), where u=k(x)/kLev, a=0.452, b=-0.625, with a maximal error of 1% in comparison with the exact solution. For the average value over the length of the slit, we propose 〈k〉/ka=(U-1)(AU-1)/(BU+1), where U=〈k〉/〈kLev〉, A=0.203, B=-0.273, with a maximal error of 0.03%. These approximations lead to an easy determination of the adsorption constant and diffusion coefficient D of the solute, as appropriate plots of experimental data provide ka and D2/3 as the intercepts of the curve with the ordinate and abscissa axes, respectively. It is pointed out that the linear approximation k-1=ka -1+kLev -1 would lead to the overestimation of both the diffusion coefficient and adsorption kinetic constant. As an example, the application to the analysis of experimental data for adsorption of α-chymotrypsin onto mica plates is provided. © 2003 Elsevier B.V. All rights reserved
Similar works
Full text
Open in the Core reader
Download PDF
Available Versions
Kazan Federal University Digital Repository
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:dspace.kpfu.ru:net/134203
Last time updated on 07/05/2019
Kazan Federal University Digital Repository
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:dspace.kpfu.ru:net/96786
Last time updated on 07/05/2019