The growing importance of interregional unions and associations in the Russian economy in the period of the current economic transformations has determined the relevance of the research topic. The changes that have been formed in Russia have an indefinite relation to the nature of the processes currently taking place in the Russian economy and in its regions. The determined transition to market relations enabled the regions to independently decide on the directions and forms of their existing resources and put aside the obligation to coordinate all steps with the capital. This, of course, is a prerequisite for the growth of the result of the functioning of the economy of the regions. Obstacles for the movement of goods and services between the subjects of Russia were formed, the process of border and customs control became more complicated. There were difficulties in the work of the railway and automobile junction. These aspects of interregional economic associations are an example of the state of the economy of certain regions, and the aspect of influence on the economy. Due to the lack of own reserves of economic growth of a particular region, the task of inter-regional economic unions and associations is being formed. Therefore, a research on improving and developing such relations in the new economic conditions becomes a viable practical goal, and solving the problem is an important element of the obstacle to crisis situations in the Russian economy and the transition to sustainable economic development