The patient was60years old, man. He is in the hospital with diabetes and spinal cord injury, admitted passing disorder, diagnosed with advanced esophageal cancer, and introduced to our hospital. Start the chemotherapy following systemic examination became operative after completion chemotherapy. Chest operation is carried out under full thoracoscopy, the end without any problems. Abdominal operation is done laparoscopy, towing the thoracic esophagus into the abdominal cavity, who developed ventricular fibrillation in a few minutes after the esophageal hiatus became a release. Immediately start cardiopulmonary resuscitation, underwent defibrillation, it was restored to the normal waveform. It was restarted operation. Reconstruction using a gastric tube, in the chest wall before route, was anastomosis in the neck. The postoperative course good, rather than after-effects and postoperative complications, and it was discharged on day 34. Esophageal cancer surgery is a highly invasive surgical procedure, there is a high frequency of arrhythmia will develop. We ventricular fibrillation develop in the esophagus resection surgery, and that a reported rare example that was life-saving