The cardiovascular disease has been increasingly recognized over the last decade. The metabolic syndrome is associated with increased risk for development of dyslipidemia leading to atherosclerosis. In addition to healthy lifestyle promotion, treatment of atherogenic dyslipidemia using lipid lowering agents such as fibrates and statins is useful. In fact, bezafibrate reduces the incidence of myocardial infarction in patients with metabolic syndrome during long-term follow-up. Early detection of atherosclerosis including endothelial dysfunction is very important strategy for preventing cardiovascular events in patients with metabolic syndrome. We attempt to establish multiphasic health testing system（Anti-Aging Medical Center : AAMC）using recently-developed devices for medical diagnosis in Tokushima University Hospital
