Ahlford, A.

Brivio, Monica

Kutter, Jörg Peter

Snakenborg, Detlef

Syvänen, A.-C

Søgaard, E.

Wolff, Anders

In this paper we present a modular lab-on-a-chip system for integrated samplepre-treatment (PT) by magnetophoresis and DNA amplification by polymerase chainreaction (PCR). It consists of a polymer-based microfluidic chip mounted on a custom-made thermocycler (Figure 1) and includes a simple and efficient method forswitching the liquid flow between the PT and PCR chamber. Purification of humangenomic DNA from EDTA-treated blood and multiplex PCR were successfully carriedout on-chip using the developed lab-on-a-chip system

On-Chip integration of sample pretreatment and Multiplex polymerase chain reaction (PCR) for DNA analysis

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Online Research Database In Technology

Online Research Database In Technology