Syntheses of melatonin and its derivatives

Abstract

金沢大学大学院自然科学研究科生理活性物質科学金沢大学薬学部Two simple synthetic methods for melatonin are newly developed from tryptamine through intermediates, which are promising lead compounds for drug developing research. Novel chemical reactivities of melatonin in its bromination, lithiation, and acylation are also reported

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