DIETARY METHODS USING LACTOBACILLUS PARACASEI SUBSP. PARACASEI F19 AS NAPE-PLD GENE CARRIER FOR PRODUCING ON DEMAND PEA OR OEA AND RELATIVE BIOLOGICAL DIETARY COMPOSITIONS THEREOF
Method enabling to modulate and customize the production of active lipids involved in exerting an antagonistic action to local inflammation and in modulating the mast cell reactivity, comprising the administering to an host the probiotic Lactobacillus paracasei subsp. Paracasei F19, genetically modified with a nucleotide vector comprising a nucleic acid encoding the human N-acyl-phosphatidylethanolamine phospholipase D (NAPE-PLD), in association with lipid substrates and precursors, to influence the enzymatic reactions of said probiotic agent in the host. The method is useful in the treatment of inflammatory bowel disorder and in the treatment of metabolic syndrome and for controlling of obesity
