Cardiac troponins are released into the bloodstream as a result of myocardial injury and their
detection in the blood is in routine clinical use for the diagnosis of myocardial infarction. A range of
other cardiac and non-cardiac conditions may also cause a rise in troponin. A number of recent
studies have found that high-sensitivity troponin is significantly associated with future coronary
events in people without prior cardiovascular disease. Some studies have investigated its
incremental benefit in risk prediction models, but have been too small to show a statistically
significant improvement in the C statistic. Nevertheless, troponin measurements should be
considered as a cardiovascular risk marker among healthy people as well as a diagnostic marker for
myocardial infarction
